Liverpool have proven they meant business in the race for another Champions League trophy after a disappointing 3-1 defeat to Real Madrid last season.
Mohamed Salah made an early opening for the Reds from a penalty set up by Sadio Mane on Moussa Sissoko.
In an evening of all-Premier League showpiece, Spurs had chances but were denied by Liverpool keeper Alisson, who saved well from Son Heung-min, Lucas Moura and Christian Eriksen.
Spurs failed to make their chances count allowing substitute Divock Origi to seal a victory for his manager Jurgen Klopp to lift his first trophy as Liverpool manager by driving low and powerfully past Hugo Lloris with three minutes left.
Mauricio Pochettino could now sit back regrettably after making a gamble to use England captain Harry Kane despite his absence since April because of an ankle injury, replacing semi-final hat-trick hero Lucas Moura.
However, Liverpool now wiped off their pains of last season lost in Ukraine and now stand behind only Real Madrid and AC Milan as serial winners of this tournament, the final whistle sparking huge celebrations among players, management and the red wave of supporters in Madrid.